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Case Study

SCOR Transformation Speeds Up Pharmaceutical Project Timelines for Roche

95% Improvement in on-time delivery performance

5 Reduction in number of days to deliver make-to-order product

50% Reduction in lead times for make-to order finished good kits

The pharmaceutical industry has faced massive changes, even before the onset of the COVID-19 pandemic. Governments have been pressuring pharmaceutical suppliers to lower costs. Increased competition has required more speed from industry players. And an explosion of personalized therapies has strained medical supply chains to deliver unique products for each patient, rather than bulk supplies of a singular product. Within this climate, Basel, Switzerland-based F. Hoffmann La-Roche Ltd. pledged to deliver twice as many medical advances at half the cost to society.

Leading the charge

Leading this charge is Roche's Pharma Technical Development Clinical Supply Chain (PTDS) team. Richard Groenenboom, head of global clinical supply chain management, says this group manages one of the largest and most complex pharmaceutical pipelines in the industry. The PTDS team typically handles more than 600 active clinical trials at any given time, and it plays a critical role in ensuring that 100,000 patients a year receive innovative new investigational medicines reliably and safely in almost every country in the world.

To push the needle even further, the PTDS team partnered with ASCM to transform the organization. The overarching goal was to better balance reliability, responsiveness, agility, cost and sustainability — key SCOR metrics categories — across operations.

Learning the SCOR language

Roche’s SCOR transformation process started in 2018 with general SCOR training and awareness sessions for all PTDS employees to help them communicate in the same business language. “Although we were successfully managing clinical trials for years with experienced people, we were not speaking the same language and did not have an end-to-end view of our processes,” explains Nathalie Mathys, business support project manager for clinical supply operations.

As a result of the training, clinical supply chain leaders have better aligned KPIs, and all PTDS employees were able to facilitate the process changes identified through the SCOR assessment.

Achieving critical synergy

Once the PTDS team had a strong knowledge foundation, team members participated in SCOR workshops. ASCM SCOR representative Douglas Kent helped the PTDS team learn about best and standard SCOR practices, analyze the state of current KPIs and performance, perform process mapping and process defect analysis, and establish roadmaps with clearly defined projects.

The relationship with ASCM and Kent, who is now the executive vice president of global strategies and alliances at ASCM, continues to provide insights about where to focus in order to achieve the desired outcomes, says Mattie Coolen, site head of clinical supply chain operations in Kaiseraugst, Switzerland. To date, the PTDS team has completed more than 20 transformation projects under Kent's coaching.

Improved vitals

The SCOR training and transformation projects delivered a variety of benefits throughout the business unit's processes, systems, tools and metrics that helped the PTDS team achieve its transformation and operational goals:

Efficiency

The organization reduced the lead time of its make-to-order finished goods kits by 50%, improved on-time delivery performance to 70% in 2019 and to more than 95% in 2020, and reduced the time for the deliver make-to-order product (sD2) SCOR process by 23%, or about five days.

Reliability

These efficiencies were achieved without sacrificing reliability or out-of-stock performance. The team made a goal to keep its stockouts to fewer than 20 per year. In 2019, the company only experienced 11 stockouts. In 2020, the company had fewer than 10 stockouts,

Formalized processes

Leaders implemented a monthly clinical demand and operations planning process as well as a project management structure within the enable SCOR stream to provide a harmonized governance structure and digital benefits realization tracking across all improvement projects. The PTDS team also added inventory and waste management processes that helped the team reduce comparator drug waste by more than $16 million. The team is on track to double that savings annually.

Clear KPIs

Better understanding of organizational and operational goals also aided the company in choosing its KPIs as well as a method for tracking performance. The PTDS team implemented the SCOR balanced scorecard as an easy-access, centralized, digital representation of a metric performance dashboard. KPIs are frequently reviewed, especially in sales and operations planning meetings, which has led to more efficient use of valuable clinical trial medicines and materials.

Clear roles and responsibilities

Once employees were all speaking the same business language and had at least a basic understanding of supply chain management and the SCOR model, company leaders were able to set clearer roles and responsibilities.

Knowledge refill

Since day one of training, the PTDS team has wanted to ensure that it could sustain all of these benefits beyond the original transformation projects. The key to this has been ongoing SCOR and APICS certification education and training, Coolen says. This gives seasoned team members the confidence to continue supporting processes as well as a renewed focus on important skills, continuous improvement and enhanced decision-making.

In addition, new employees receive SCOR training as part of their onboarding process so that they can best collaborate with their cohorts right from the start of their Roche careers. Possibly the most important benefit of this training, according to Coolen, is that it gives employees the motivation to continue to find ways to deliver new medicines for patients in a better, faster and more efficient way. This enables Roche to improve its processes and practices to support the fast-evolving pharmaceutical industry and deliver medical treatments to patients around the world.

Roche Case Study

Award Winner

Check out the interview about the organization's journey to become winners of the ASCM Award of Excellence - Corporate Transformation.

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